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Canadian anti-inflammatory drug colchicine reduces COVID-19-related complications and mortality: Research-Technology News, Firstpost

Major clinical trials in Canada have shown that a cheap anti-inflammatory drug called colchicine significantly reduces the risk of complications and death from Covid-19 and provides “significant hope” for patients. Jean-Claude Tardif, head of the Montreal Heart Institute (ICM), led a study named “Colcorona”, the preliminary results of which were announced Friday night.The full results will be published “as soon as possible,” he said in an interview. AFP..

Colchicine is a powerful anti-inflammatory drug that has been known for a very long time and was discovered 150 years ago. Extracted from a plant called autumn crocus, it is used to treat various diseases such as gout, inflammatory arthritis and pericarditis. Representative image.

Q: What are the main conclusions of your study conducted on 4,488 patients worldwide since March 2020?

A: The Corcorona study provided convincing results that colchicine-related Covid-19 hospitalizations or deaths were reduced by more than 20% compared to placebo … officially demonstrating Covid-19. When dealing with patients who have been tested, the results with colchicine are even better in diagnosis. That is, a 25% reduction in hospitalization, a 50% reduction in the need for ventilation, and a 44% reduction in death.

The hypothesis behind the study was that the reason patients develop complications from Covid is an exaggerated inflammatory response in which their white blood cells develop in response to the virus … our intuition is You can prevent complications, known as “cytocytosis storms,” ​​which were to reduce this exaggerated inflammatory response by using drugs like corhitin.

Q: Why do you think results are so important in the global battle against pandemics?

A: Colchicine is a powerful anti-inflammatory drug that has been known for a very long time and was discovered 150 years ago.It is extracted from a plant called Autumn crocus It is used to treat various diseases such as gout, inflammatory arthritis and pericarditis.

The beauty of the results of this study is that colchicine is already available in pharmacies because it is used safely and cheaply for many diseases … Our findings are in France, Canada, Not only the United States and G8 countries, but also developing countries, poor countries, Africa and Asia will soon benefit from cheap colchicine taken orally in the form of tablets.

Our results bring important hope to patients, healthcare systems and governments. Finally, it offers some of the key solutions to reduce hospitalization and ultimately reduce congestion in the hospital system.

Q: Scientists are waiting for the full results of your research, when are you planning to publish it?

A: Today (Sunday), we will submit the manuscript to major scientific journals. I obviously can’t guess the publication date, the journal does its job, it’s one of the largest journals in the world. Share the rest of the results as soon as possible, perhaps even before the final publication (journal). We are confident that our results are decisive and compelling and can be used immediately to benefit patients.

Perhaps there is a quick review by regulators, the EMA (European Medicines Agency), Health Canada in Canada, and the FDA in the US, and we’ll review the data quickly … I don’t think doctors need to wait now. This regulatory review … Physicians, healthcare professionals are already available and can be prescribed immediately.



Canadian anti-inflammatory drug colchicine reduces COVID-19-related complications and mortality: Research-Technology News, Firstpost

Source link Canadian anti-inflammatory drug colchicine reduces COVID-19-related complications and mortality: Research-Technology News, Firstpost

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