Washington [US], October 14 (ANI): A new study found that eating highly processed foods for 4 weeks resulted in a strong inflammatory response in the brain of aged rats with behavioral signs of memory loss. rice field.
Researchers have also found that supplementing processed diets with the omega-3 fatty acid DHA prevents memory problems and almost completely reduces the inflammatory effects of older rats. This study was published in the journals Brain, Behavior, and Immunity.
Neuroinflammation and cognitive problems were not detected in young adult rats that ate a processed diet.
Research diets mimic ready-to-eat human foods that are often packaged for long shelf life, such as potato chips and other snacks, frozen entries such as pasta dishes and pizzas, and preservative-containing deli meats. Did.
Highly processed diets are also associated with obesity and type 2 diabetes, and older consumers may want to reduce convenience foods and add DHA-rich foods such as salmon to their diets, researchers say. Says. The study was revealed in just four weeks.
Ruth Varientos, a researcher at the Institute of Behavioral Medicine at Ohio State University and an associate professor of psychiatry and behavioral health, said:
“These findings show that eating processed foods can cause serious and sudden memory loss. In an aging society, rapid memory loss progresses to neurodegenerative diseases such as Alzheimer’s disease. By recognizing this, we will probably be able to limit processed foods in the diet, increase consumption of foods rich in omega-3 fatty acids DHA, and prevent their progression. Or delay. ”In the Varientos laboratory, we study daily life events such as surgery and infectious diseases. If an unhealthy diet can cause inflammation of the aging brain, especially focusing on the hippocampus and Amigdara areas. This study suggests that a short-term high-fat diet may lead to memory loss and brain inflammation in older animals, and that DHA levels are lower in the hippocampus and amygdala of older rat brains, according to her previous study. Is based.
DHA, or docosahexaenoic acid, is an omega-3 fatty acid that is present with eicosapentaenoic acid (EPA) in fish and other seafood. Among the multiple functions of DHA in the brain is the role of fending off the inflammatory response. This is the first study of its ability to act on brain inflammation caused by processed diets.
The researchers randomly assigned 3-month-old and 24-month-old male rats to a normal diet (32 percent from protein, 54 percent from wheat-based complex carbohydrates, and 14 percent from fat). Processed diet (19.6% of calories from protein, 63.3% from refined carbohydrates (cornstarch, maltodextrin, sucrose), 17.1% from fat), or the same processed diet with DHA added.
Activation of potent pro-inflammatory proteins and genes associated with other pro-inflammatory markers in aged rats that ate only processed diets compared to young rats fed any diet and older rats supplemented with DHA. Significantly elevated in hippocampus and amygdala. processed food.
Older rats fed a treated diet also showed signs of memory loss in behavioral experiments that were not apparent in younger rats. They forget that they spent less than a few days in an unfamiliar space, a sign of a problem with hippocampal contextual memory, and anticipatory fear of dangerous cues suggesting an abnormality in the amygdala. Did not show any action.
“The human amygdala is involved in memory associated with emotional (creating fear and anxiety) events. When this area of the brain is dysfunctional, clues to predict danger are overlooked, leading to bad decisions. It’s possible, “Variantos said.
The results also showed that dietary DHA supplementation of processed foods ingested by older rats effectively prevented elevated inflammatory responses in the brain and behavioral signs of memory loss.
Researchers do not know the exact dose of DHA ingested by an animal, or the exact calories and nutrients. All of these had unlimited food access. Both age groups gained significant weight on processed diets, with older animals gaining significantly more weight than younger animals. DHA supplementation did not prevent weight gain associated with eating highly processed foods.
That was an important discovery. Varientos warned that consumers would interpret the results as a license to enjoy processed foods as long as they were taking DHA supplements. A better bet to prevent multiple adverse effects of highly refined foods would focus on improving the overall diet, she said.
“These are the types of diets that are advertised as low-fat, but they are highly processed. They are fiber-free and contain refined carbohydrates, also known as low-quality carbohydrates. “She said. “People who are accustomed to viewing nutritional information need to pay attention to the fiber and quality of carbohydrates. This study really shows that they are important.” This study is from the National Dental Institute. Supported by the National Institute of Dental and Facial Research. Research, and Ohio Agricultural Research and Development Center. Co-authors include Michael Butler, Nicholas Deems, Stephanie Muscat, Martha Belury of The Ohio State University, and Innotiv Inc of Boulder, Colorado. Includes Christopher Butt. (ANI)
Highly processed foods affect memory: research
Source link Highly processed foods affect memory: research